Albumin binding probe for extending the lifetime of drugs. Most polypeptide drugs, in particular non-glycosylated proteins of molecular mass less than 50 kDa, are short-lived species in vivo having circulatory half lives of 5-20 min. Drug association with endogenous albumin may be suitable for desig.....
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Need:There is a need for novel compounds with anti-biofilm activity to increase susceptibility of certain bacterial strains towards conventional antibiotics. Innovation:We have developed novel compounds with anti-biofilm activity. We are proposing to use our compounds as a potential anti-biofilm str.....
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A method or device for illuminating the biliary tree utilizing differential light absorption of biliary ducts and surrounding tissuesLaparoscopic cholecystectomy is a minimally invasive procedure for gallbladder removal surgery. Over 750,000 cholecystectomy procedures are carried out each year in th.....
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Laser beam shaping is a key element in achieving better accuracy and resolution. Currently, there are two main methods for shaping a beam: one method uses two lenses to output a homogeneous beam with no power control. This method requires time consuming calibration of the lenses and can not accept o.....
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Animal eye models for evaluation of systemic and topical use of new medications, devices and delivery systems. The models include external eye, intraocular, orbital, and optic nerve applications.
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