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Method to Enhance the Efficiency of Systemic AAV Gene Delivery to the Central Nervous System

This invention relates to compositions and methods for increased efficiency of gene transfer to the CNS. The invention is based on the surprising discovery that viral vector-mediated delivery of nucle [Detail]

Tags: CNS AAV gene therapy Gene Delivery hsv Brain blood brain barrier Viral Vectors

Microfabricated Silicon-Based Hollow Microneedles with Integrated Fluid Channels for Transdermal Fluid

Improved delivery of drugs or other substances through a surfaceContinuous in situ sampling without the complications of lancetsCustomized lengths for access to interstitial fluid bathing the epidermal cells (200-250 micron length) or whole blood from dermal capillaries (250-350 micron length)Micron..... [Detail]

Tags: Other Devices Research Tools microneedle

Molecular Detection, Imaging and Targeted Therapy for Invasive and Metastatic Cancer

None [Detail]

Tags: biomarkers nanoparticles cancer diagnostics gliomas glioblastomas glioblastoma multiforme GBM tumor recognition cancer therapeutics receptor protein tyrosine phosphatase PTPmu melanoma prostate cancer lung cancer

Natriuretic Peptide Receptor as a Biomarker for Cancer

None [Detail]

Tags: none

Near-Field Diffractive Microscope

A near-field microscope using one or more diffractive elements placed in the near-field of an object to be imaged. A diffractive covers the entire object, thus signal may thereby be gathered from the [Detail]

Tags: Engineering optics Microscopy

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