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Docket # 17-3362 Although considerable progress has been made in understanding the genetic basis of morphologic traits (e.g. body size, coat color) in dogs and wolves, the genetic basis of their behavioral divergence is poorly understood. Researchers at Princeton University have conducted a genome-w..... [Detail]
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The intellectual property relates to beta- or alpha-cell specific single chain antibodies (SCAs) that enable the specific and non-invasive transport of a selected therapeutic agent to pancreatic islet - or α-cells. [Detail]
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Project ID: D2013-04Novelty: A new class of anticancer agents which are highly selective for mesenchymal cancer cells with stem cell like properties.Effective management of advanced cancer requires systemic treatment including small molecules that target unique features of aggressive tumor cells. At..... [Detail]
• Small molecules are more readily scaled and controlled in drug development (vs. proteins and peptides)• TLR-4 specificity allows one to modulate the immune response in a more cell-specific manner• Small molecules easily modified to enable linking to other TLR-agonists for combined drugs [Detail]
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