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A novel high throughput screening assay for identifying inhibitors of nuclear import based on a roboticised amplified luminescent proximity homogeneous assay technology. [Detail]
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- Simultaneously high spatial, voltaic, and temporal resolutions - Large-scale parallel imaging of electric fields, voltage, acidity, strain, and bioelectric dynamics - Compatible with simultaneous, complementary microscopy measurements - Operates under a wide range of chemical and thermal conditio..... [Detail]
Lead Inventors: Stephen Bennett Johnson, David Campbell, Eneida Mendonca, Robert Duffy, Chunhua Weng.Problem or Unmet Need:Biomedical natural language parsing software converts free-form prose from medical reports to a structured form that can be processed by information retrieval and other analytic..... [Detail]
A novel target for cancer therapy ARF has tumor suppressor activity that is p53 independent Since ARF-BP1 interacts with ARF and p53 but not with Mdm2, it is a useful therapeutic target in tumors that lack Mdm2 activity [Detail]
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