Reduces adiposity without elevating plasma triglyceride levelsImproves glucose homeostasis by several potential mechanisms and directly targets both white and brown adipose tissue
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The tetracyclic structure of indolo[3,2-b]quinolines, also referred to as quindoline (1) constitutes as important structural moiety in the literature because of its effect on numerous biological functions.
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Extended half-life/higher stabilitySmall molecular weight allows for delivery of more active ingredient per dose Modification is not known to induce immune response or hypersensitivity in humansCan be efficiently synthesized in large quantities using well established protocols
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This technology originates from identification of a deep intronic mutation in Dysferlin (DYSF) that alters mRNA splicing to include a mutant peptide fragment within a key DYSF domain. This new antisen
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