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Efficient therapy to treat hormone resistant tumorSelective inhibition of prostate cancer cellsProvides a specific drug target against an extremely difficult-to-treat cancerExtensive cancerous cell death upon administration [Detail]
The methods/compositions:ΓÇóEnable differentiation of stem/progenitor cells into oocytes and/or eggsΓÇóCan be applied both ex vivo or in vivo or as a combination to maximize desired outcomesΓÇóProvide a non-invasive procedure to increase oocyte numbers in the ovariesΓÇóAvoid use of potentially harmf..... [Detail]
PROTAC technology is emerging as a novel therapeutic method to target diseases caused by the abnormal expression of a disease-causing proteins. PROTACs simultaneously bind a target protein and its E3-ubiquitin ligase, causing ubiquitination and degradation of the target protein. Studying protein-pro..... [Detail]
This new system leads to optimal or near-optimal designs with greatly simplified routing architecture. Compared with other methods, it offers: Improved circuit performance due to automatic optimal wire width planning; Better control of performance and area trade-off given the method's flexibility i..... [Detail]
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