將細胞粘著強化劑從媒介物均勻涂敷到多孔骨架或管道孔壁表面的方法
The invention provides a method for coating cell agglutination enhancer on the hole wall surfaces of porous frame or pipeline made of natural or synthetic material. The method comprises the followingsteps: coating one or more cell agglutination enhancers on a medium surface and molding the medium; casting the natural or synthetic frame material on the molded medium with a coating; removing the medium material and transferring the cell agglutination enhancer uniformly from the medium surface to the hole wall surface of the porous frame. The cell agglutination enhancer is inlaid in the hole wall surface, even embedded inside the frame substrate. The coating structure can increase coating strength between the coating material and the frame. The coating enables the frame to have cell recognition signal, improves seeding, distribution and reproduction of cells, and facilitates formation of new tissue and blood vessel. The method can be applied according to different tissue engineering requirements to carry out coating and modification on surfaces of porous frame or pipeline with respective coating material.
Inventor: Jiashen Li | Fuda Mai
Priority Number: CN101116755B
IPC Current: A61L002728
Assignee Applicant: The Hong Kong Polytechnic University
Title: Method for evenly coating cell adhesion hardening agent from intermediate medium to the stephanoporate framework or the pipe hole wall surface | Method to cell adhesion enhancer from medium is evenly coated to porous skeleton or surface of pipe hole
Usefulness: Method for evenly coating cell adhesion hardening agent from intermediate medium to the stephanoporate framework or the pipe hole wall surface | Method to cell adhesion enhancer from medium is evenly coated to porous skeleton or surface of pipe hole
Summary: Method for coating a cell agglutination energizing agent e.g. liquid, for porous skeleton or surface of a pipe hole wall from an inter media e.g. sodium chloride (all claimed).
Novelty: Cell agglutination energizing agent e.g. liquid, coating method for porous skeleton or surface of pipe hole wall, involves transferring cell agglutination energizing agent to surface of hole wall of skeleton from surface of inter media
生物医学
复康
LI Jiashen
MAK F.T., Arthur
中国内地
