亞洲知識產權資訊網為知識產權業界提供一個一站式網上交易平台，協助業界發掘知識產權貿易商機，並與環球知識產權業界建立聯繫。無論你是知識產權擁有者正在出售您的知識產權，或是製造商需要購買技術以提高操作效能，又或是知識產權配套服務供應商，你將會從本網站發掘到有用的知識產權貿易資訊。

返回搜索結果

CLAC3A

總結: The cartilage-specific CLEC3A has antimicrobial activity against some of the most common nosocomial bacteria with lack of own immunogenicity and is suitable for surface coating of prostheses.

技術優勢: Potent antibiotic activity against both Gram-positive and Gram-negative nosocomial Bacteria
No immunogenicity due to the protein`s natural expression in cartilage
No cytotoxicity against human cell
Suitable for surface coating of prostheses and dental implants

技術應用: Reducing infections such as those from joint replacement and dental implant surgery.

詳細技術說明: peptides of the cartilage-specific CLEC3A kill both Gram-positive and Gram-negative nosocomial bacteria (Figure A). Furthermore, coating these antimicrobial peptides on titanium substrates significantly reduces bacterial adhesion on titanium substrates (Figure B). Coating of prostheses and dental implants with CLEC3A-derived antimicrobial peptides could therefore be an effective way of preventing infection without cytotoxicity and immunogenicity issues.

欲了解更多信息，請點擊這裡