A PROCESS AND MATERIAL FOR SEALING FAYING SURFACES OF LAP JOINTS FORMED BY FRICTION STIR WELDING
None
Inventor: Satchi Fainaro, Ronit | Folkman, Judah
Priority Number: US6949584B2
IPC Current: A61K0031785 | A61K0039395 | A61K004500 | A61K004748 | A61P000900 | A61P003500 | C07D030322
US Class: 514475 | 549332
Assignee Applicant: Children's Medical Center Corporation,Boston
Title: TNP-470 species, polymer conjugates and use thereof
Usefulness: TNP-470 species, polymer conjugates and use thereof
Summary: The composition is used for treating angiogenic diseases and decreasing neurotoxicity of TNP-470 (claimed). The angiogenic diseases can be diabetic retinopathy, macular degeneration, retrolental fibroplasia, trachoma, neovascular glaucoma, psoriases, angio-fibromas, immune and non-immune inflammation, capillary formation within atherosclerotic plaques, hemangiomas, excessive wound repair, solid tumors, metastases, and Kaposi's sarcoma.
Novelty: Conjugated-polymer containing composition for treating angiogenic diseases e.g. diabetic retinopathy, macular degeneration, or retrolental fibroplasia, comprises O-(chloracetyl-carbamoyl) fumagillol conjugated to water-soluble polymer
生物醫學
醫藥成分
美國
