Diagnosis of osteoarthritis
- 总结
- First serum biomarker test based on thrombospondin-4 autoantibodies that helps to support the clinical diagnosis of osteoarthritis.
- 技术优势
- First biomarker of osteoarthritis
- 技术应用
- The first serum biomarker test that helps to support the clinical diagnosis of osteoarthritis and furthermore may provide a tool that allows the monitoring of therapeutic success of drug candidates for the treatment of arthrosis.
- 详细技术说明
- Autoantibodies against the cartilage protein thrombospondin 4 (TSP-4) occur in the course of arthrosis. Rheumatoid arthritis is characterized by the presence of autoantibodies, but autoantibodies against TSP-4 have jet not been described for arthrosis. In addition to TSP-4, the researchers have found autoantibodies against the cartilage oligomeric matrix protein (COMP) and the C-type lectin domain family 3 member A (CLEC3A) in the course of OA, which may be used in a combined test together with TSP-4 in order to strengthen significance of diagnosis
- 合作类型
- Licensing
- 申请日期
- 12/12/2018 00:00:00
- 申请号码
- WO2018EP84451 20181212
- 分类
- - international:
G01N33/564
- cooperative:
G01N33/564; G01N2800/105
- 其他
- Patent application
- ID号码
- 4812
- 国家/地区
- 德国
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