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Antibodies against human CEACAM1 gemeinsam mit 4782

总结

Monoclonal antibodies for research, which are specific for CEACAM1. In contrast to available antibodies the two antibodies exhibit a high affinity and specificity for the A1/B-domains of human CEACAM1 and do not bind to other members of the family of CEACAM-family.

技术优势

Monoclonal antibody directed against the A1/B-domains of human CEACAM1
High affinity and mono-specificity
Detect membrane anchored and soluble human CEACAM1 and most of its derivatives
Suitable for numerous applications:
> in cancer research
> in diagnosis
> in therapy monitoring
>as immunmodulator in the therapy of tumors, infections and inflammations

技术应用

Suitable to detect the membrane anchored, the cleaved soluble CEACAM1 and most of its derivatives. It is of use in several research applications, including ELISA, WB, IP, IHC, fluorescence microscopy and flow cytometry.

详细技术说明

Due to the structural similarity it is very challenging to obtain antibodies against specific CEACAM1-domains. CEACAM1 has been detected at elevated levels in the surrounding tissue of tumors and the tumors themselves. It appears that CEACAM1 is a suitable biomarker for the diagnosis and staging of tumors.

合作类型

Licensing

申请日期

22/06/2010 00:00:00

申请号码

DE20101024636 20100622

分类

- international:
C07K16/28; C12N5/12; G01N33/53
- cooperative:
C07K16/30; M68G01N33/K6957434; G01N2333/70596

其他

Patent application

ID号码

2401

国家/地区

德国