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Pseudoprolines in Neuropeptides

详细技术说明: Title: Development of Novel Pseudopeptides Invention: The invention describes the use of pseudo peptides to cross the blood-brain barrier and bind to targeted receptors to achieve pharmaceutical effects. Background: Increased research has led to the exploration of peptides delivering compounds by diffusing across the blood-brain barrier. Many peptide-based drugs are not created using pseudo-peptides, however, glycosylation plays a key role in manipulating the structure of existing peptides. This invention uses glycosylation to create a newly folded peptide that can then be used in a variety of pharmaceutical applications to produce medicinal effects. Applications: Targeted drug deliveryBiosensors Diagnostic imaging Advantages: Increased capability to cross the blood-brain barrier Increased affinity to bind to specific targeted receptors Breakdown of the compound may not yield any toxic effects Licensing Manager:Laura SilvaLauraS@tla.arizona.edu(520) 626-1557

*Principal Investigation: Name: Robin Polt, Professor
Department: Chemistry & Biochemistry

Name: Evan Jones, Graduate Assistant
Department: Chemistry & Biochemistry

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