亚洲知识产权资讯网为知识产权业界提供一个一站式网上交易平台，协助业界发掘知识产权贸易商机，并与环球知识产权业界建立联系。无论你是知识产权拥有者正在出售您的知识产权，或是制造商需要购买技术以提高操作效能，又或是知识产权配套服务供应商，你将会从本网站发掘到有用的知识产权贸易资讯。

返回搜索结果

Natural Products for Cancer Therapeutics

详细技术说明: Although algorithms and chemistries for developing new therapeutic entities are constantly evolving, none can replicate the path and novelty of natural selection over eons of time. Inventors at the Scripps Institution of Oceanography have engaged their fleet of research ships to cull the oceans for marine organisms from which new compositions are isolated. Using a variety of culture systems, selective fractionation and bioassays, two, distinct classes of compounds, isolated from actinomycetes, have demonstrated potent anti-tumor activity and considerable selectivity toward some cancers. One class of compounds, the ammosamides, are unique molecules that target a previously untargeted intracellular pathway. It is anticipated that proprietary methods and naturally evolved compositions may yield therapeutics that are significantly differentiated from those developed by limited iteration of pre-defined platforms.

*Principal Investigation: Name: William Fenical
Department:

Name: Chambers Hughes
Department:

Name: Paul Jensen
Department:

Name: James La Clair
Department:

Name: John MacMillan
Department:

附加资料: Patent Number: US8133902B2
Application Number: US2010666269A
Inventor: Fenical, William | Jensen, Paul | MacMillan, John | Hughes, Chambers C. | LaClair, James J.
Priority Date: 29 Jun 2007
Priority Number: US8133902B2
Application Date: 23 Dec 2010
Publication Date: 13 Mar 2012
IPC Current: A61K0031437 | C07D047106
US Class: 514296 | 546081 | 546084
Assignee Applicant: The Regents of the University of California
Title: Ammosamides as anticancer agents
Usefulness: Ammosamides as anticancer agents
Summary: In a pharmaceutical composition; for inhibiting proliferation of mammalian cells; and for treating a mammalian cell proliferative disorder selected from colon cancer (all claimed), head and neck cancer, brain cancer, breast cancer, colorectal cancer, esophageal cancer, gastric cancer, hepatic cancer, bladder cancer, cervical cancer, endometrial cancer, lung cancer, ovarian cancer, gynecological cancers, pancreatic cancer, prostate cancer, renal cancer, lung cancer, skin cancer. Also useful for treating tumor.
Novelty: New ammosamide compound useful in the treatment of cancer e.g. colon cancer, head and neck cancer, brain cancer, breast cancer, colorectal cancer, esophageal cancer, gastric cancer