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Cure of CLL

Summary
Derivatives of para-nitric oxide-donating acetylsalicylic acid provide novel compounds for the treatment of CLL.
Technology Benefits
Compound claims towards novel derivatives of para-NO-ASA: High selectivity, high activity, tested on different CLL cell populations, proven in a xenograft model of CLL
Development team comprising chemists and clinicians
Compounds may be suitable for the treatment of other neoplasias
Technology Application
effective and selective medicament for the treatment of neoplastic diseases or proliferative disorders
Detailed Technology Description
The present invention provides compounds acting as an effective and selective medicament for the treatment of neoplastic diseases or proliferative disorders, in particular compounds which induce selectively apoptosis of degenerated cells providing reduced side effects in living organisms
Type of Cooperation
Licensing
Application Date
24/09/2014 00:00:00
Application No.
EP20140771921 20140924
Classes
- international:
A61K31/621; A61K31/695; A61P35/00; A61P35/02; C07C203/04; C07C247/10; C07C309/76; C07C69/76; C07F7/08
- cooperative:
A61K31/215; A61K31/235; A61K31/24; A61K31/621; C07C203/04; C07C247/10; C07C309/76; C07C69/75; C07C69/76; C07C69/78; C07C69/86; C07F7/081; C07F7/1804; C07C2601/14
Others
Patent application
ID No.
4045
Country/Region
Germany

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