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Manipulating and Detecting Particles and Molecules

Detailed Technology Description
Graphene Electrodes Sensing Small MoleculesAtomically thin surfaces, such as the edges of 2D materials like graphene, can be used as graphene electrodes in dielectrophoresis for sensing and trapping small particles and molecules. Specifically, the atomically sharp 2D graphene edges act as a “lightning rod” for electrical and optical fields. Upon biasing such electrodes, particles or molecules suspended in a solution will be rapidly attracted and trapped alongside their sharp edges. Advantages of this technology are potentially higher sensitivity, rapid detection and tunable optical properties. The edges are sensitive spots for electrical, optical, or chemical detection of such objects, making this technology very attractive for biochemical sensing. The trapping scheme can serve as optical, electrical, electrochemical or plasmonic sensors by integrating them into lab-on-chip devices, chip-based arrays or other electronics.2D Graphene ElectrodesDielectrophoretic or electrokinetic trapping of biological objects currently uses micro- or macroscale metal electrodes, which limit detection ability. Other methods, such as fabricating carbon nanotube (CNT) or other nanomaterials with sharp edges, has proved difficult. This approach uses 2D graphene materials as multifunctional electrodes. Sensors based on edges of monolayer graphene trap and detect DNA and nanodiamonds particles via dielectrophoresis (DEP). Another advantage is that graphene edges can be reproducibly prepared.BENEFITS AND FEATURES:Selective trapping of nanoparticles and molecules, tunable sensing of moleculesAtomically thick electrodesIntegrated into lab-on-chip and solid state sensor devicesPotentially higher sensitivityRapid detectionFlexible and tunable optical propertiesAPPLICATIONS:Biosensors; platform biosensing technology (e.g., nanopore DNA sequencing)Sensing and trapping small particles and moleculesDiagnostic chipsOptical, chemical, electrical, electrochemical or plasmonic sensor platformsPhase of Development - Prototype development/working prototype

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