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Improved Immunogenicity for Attenuated Respiratory Syncytial Virus Vaccines

Technology Benefits
Enhanced immunogenicity, Increased genotypic and phenotypic stability, Able to replicate to high titers in suitable cell substrates for vaccine production
Detailed Technology Description
Our invention provides a method for producing live attenuatedRSV vaccine candidates with enhanced immunogenicity without compromising the ability of the virus to replicate to high titers in suitable cell substrates for vaccine production. This new method has to potential to provide the first license vaccine for RSV since its discovery and provide a much needed preventative treatment for pediatric bronchiolitis.
*Abstract
Researchers at the University of South Florida have developed a method to produce live attenuated RSV vaccine candidates with improved immunogenicity and stability.
Country/Region
USA

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