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Nanoparticles for the Treatment of Neurodegenerative Diseases and Cancer

Technology Benefits: Able to cross the blood-brain barrierDecreased renal toxicity

Technology Application: alzheimer's treatment,neurodegenerative disease treatment, cancer treatment, treatment, drug delivery of biocompatible and biodegradable PLA-PEG and PLGA-PEG nanoparticles

Detailed Technology Description: Our inventorΓÇÖs have generated a novel MKT-077 formulation based nanoparticles to overcome the renal toxicity and BBB transport issues associated with the drug. These nanoparticles have shown BBB permeability and tau reduction in lab basedexperimental models. This MKT-077 loaded polymer nanoparticle offers a novel treatment modality for AlzheimerΓÇÖs Disease, as well as other neurodegenerative diseases, and may even be effective in the treatment of certain cancers.

*Abstract: Researchers at the University of South Florida have developed novel MKT-077nanoparticles for the treatment of AlzheimerΓÇÖs disease, other neurodegenerative diseases, and cancer.

Country/Region: USA

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