Polyrad - Prolonging Shelf Life of Space Medications
- Detailed Technology Description
- None
- Others
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- *Abstract
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A radiation resistant drug delivery system is designed using free radical scavenging molecules and biocompatible polymers for prolonged pharmaceutical shelf life in a space-mimicking environment. Maintaining the structural and functional activity of pharmaceutical drugs aboard of International Space Station (ISS) under spaceflight environment of cosmic radiation, carbon dioxide rich atmosphere (2% CO2 by volume compared to 0.03% on earth), humidity and temperature is one of the biggest challenges. Melatonin is encapsulated inside a biocompatible polymeric nanoparticle that includes free radical scavenging agents conjugated with the surface to enhance the stability of drugs in space.
- *Principal Investigator
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Name: Sutapa Barua, Assistant Professor
Department:
Name: Hannah Kim, Undergraduate Researcher
Department:
- Country/Region
- USA
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