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Direct and Efficient Synthesis of Poly(3-Hydroxybutyrate)

Detailed Technology Description
None
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Publication:

Dunn, E. W.; Coates, G. W. Carbonylative Polymerization of Propylene Oxide: A Multicatalytic Approach to the Synthesis of Poly(3-Hydroxybutyrate). J. Am. Chem. Soc. 2010, 132, 11412-11413. doi: 10.1021/ja1049862

*Abstract

A direct and highly efficient, one-pot method for the synthesis of poly(3-hydroxybutyrate) (P3HB) from epoxides and CO. This process eliminates the need for purification of the toxic lactone intermediate.

Poly(3-hydroxybutyrate) is a naturally occurring biodegradable and biocompatible polyester that exhibits properties similar to polyolefins. The current processes for production result in low molecular weight polymers, are energy-intensive and necessitate polymer separation from the bacterial culture used for synthesis.

Potential Commercial Application:

  • For commercial production of P3HB.
*Licensing
Jeff Fearn, Senior Technology Commercialization and Liaison Officerjcf55@cornell.edu607-254-4502
Country/Region
USA

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