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Single Step Polymerization Of Covalently Bound Multilayer Matrices

Detailed Technology Description

University researchers have developed a density gradient multilayer polymerization (DGMP) method to fabricate multicompartment hydrogels. The technique is accessible, versatile, and facilitates control of discrete, as well as continuously graduated, mechanical and chemical interfaces within structurally uninterrupted hydrogel networks. DGMP can be combined with a multitude of current fabrication paradigms to increase the complexity of matrices for tissue engineering/scaffolds, controlled drug delivery, or biological investigation.

Supplementary Information

Inventor: Sigmund, Wolfgang M. | Spatz, Joachim
Priority Number: US7851056B2
IPC Current: B32B002900 | B05D000118 | B05D000508 | B08B001702 | B08B001706 | B81B000300 | B82B000100 | B82B000300 | C01B003102 | C03C001700 | C04B004152 | D03D001500 | B05D000116
US Class: 4282951 | 427212 | 4282974 | 4282981 | 428403 | 428500
Assignee Applicant: University of Florida Research Foundation Inc.inesville
Title: Ultralyophobe interfaces
Usefulness: Ultralyophobe interfaces
Summary: In production of self-cleaning and/or non-wetting surfaces such as paints or other surface coatings used for automobiles and buildings, for applying to glass to produce self-cleaning windows or window shields.
Novelty: Lyophobic surface used in production of self-cleaning/non-wetting surfaces e.g. paint comprises flexible fibers bound to bonding layer and having ratio of elastic modulus to aspect ratio such that fibers bend upon contact of liquid surface

Industry

Chemical/Material

Sub Category

Chemical/Material Application

Application No.

9409322

Others

Intellectual Property Info

This invention has a patent pending and is available for licensing.

Related Materials

New Method Makes Culture Of Complex Tissue Possible In Any Lab
Density Gradient Multilayer Polymerization for Creating Complex Tissue Advanced Materials, Volume 24, Issue 11, pages 1466–1470, March 15, 2012

Tech ID/UC Case

22950/2012-056-0

Related Cases

2012-056-0

*Abstract

Tissue engineering has recently focused on biomimetic matrices, usually polymer hydrogels, that include multiple layers with distinct structures and chemical components. Current methods of fabricating such matrices are complex or expensive to implement and often produce mechanical weaknesses between layers. Thus, an adaptable, facile, and economical multilayer polymer fabrication technique that produces continuous interfaces between layers is needed.

*IP Issue Date

Aug 9, 2016

*Principal Investigator

Name: Adah Almutairi

Department:

Name: Jerome Karpiak

Department:

Name: Jose Morachis

Department:

Name: Yogesh Ner

Department:

Country/Region

USA