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Annular Laser Trap for Cell Sorting and Behavior Analysis

Detailed Technology Description
Researchers in the School of Engineering at The University of California, San Diego, have invented a novel laser trapping technique for manipulating, analyzing and parallel sorting of self-propelled cells (sperm, algae, bacteria) based on mobility and biotropism. A unique optical design is used to create a tunable 3-D annular trap (tens to hundreds of microns in diameter) with high-power efficiency and constant numerical aperture. The laser trap only provides optical confinement in the radial direction.  The design is different than the single spot laser trap which focuses hundreds of milli-watts to immobilize a single sperm; the annular trap can be used to investigate and sort tens to hundreds of sperm in parallel, and distributes only tens of milli-watts on a sperm to allow study of sperm dynamics.  A functioning optical apparatus has been assembled and has yielded preliminary experimental data.
Others

State Of Development

The Technology is in early-stage development, and licensing is presently available.


Tech ID/UC Case

19807/2007-192-0


Related Cases

2007-192-0

*Abstract
None
*Principal Investigator

Name: Michael Berns

Department:


Name: Sadik Esener

Department:


Name: Bing Shao

Department:

Country/Region
USA

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