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Three-Dimensional Breast Anatomy Imaging System

Technology Application
One of the advantages of this imaging system is the accuracy with which it can image breast tissue and monitor subsequent changes throughout the course of therapy. With this breast anatomy imaging system, clinicians can overcome the limitation of conventional technologies and accurately track the position of the optical probe as measurements are recorded. This will improve the clinician’s ability to measure the same region of interest and increase the measurement sensitivity by minimizing uncertainties involved with optical handheld probe position placement.
Detailed Technology Description
None
Supplementary Information
Patent Number: US8244332B2
Application Number: US2005292338A
Inventor: Azar, Fred S. | Khamene, Ali | Sauer, Frank | Tromberg, Bruce | Cerussi, Albert
Priority Date: 22 Dec 2004
Priority Number: US8244332B2
Application Date: 1 Dec 2005
Publication Date: 14 Aug 2012
IPC Current: A61B000600
US Class: 600476 | 600310 | 600473
Assignee Applicant: Siemens Medical Solutions USA Inc.lvern,PA
Title: Three-dimensional breast anatomy imaging system
Usefulness: Three-dimensional breast anatomy imaging system
Summary: Diffuse optical spectroscopy system for breast scanning for use in pre-operative chemotherapy.
Novelty: Diffuse optical spectroscopy system for breast scanning, especially for use in pre-operative chemotherapy, has a hand-held probe that is used to scan the breast and is connected to a spatial tracking device
Industry
Disease Diagnostic/Treatment
Sub Category
Cancer/Tumor
Application No.
8244332
Others

Background

Pres-surgical chemotherapy is a treatment commonly used for locally advanced breast cancer. The patient’s response to the pre-surgical chemotherapy is monitored to improve survival and reduce morbidity. In order to accurately distinguish between tumor and surrounding breast tissue, a method that can quantitatively monitor tumor response to this chemotherapy needs to be developed.


Tech ID/UC Case

20688/2007-126-0


Related Cases

2007-126-0

*Abstract

Researchers at the University of California, Irvine have developed a breast anatomy imaging system that combines a position tracking system with a handheld optical imaging device. This combined technology allows the researcher and/or clinician to image cancerous versus normal breast tissue at intervals throughout the course of the therapy. A non-invasive near-infrared technology based upon diffuse optical spectroscopy (DOS) has been developed to quantitatively monitor tumor response to the pres-surgical chemotherapy. A tracking device associated with a handheld device can measure a region of interest in the breast tissue at each visit with approximately 1 mm system accuracy. Thus, diffuse optical spectroscopy is used to monitor tumor response in patients with locally advanced cancer throughout the course of the therapy.

*IP Issue Date
Aug 14, 2012
*Principal Investigator

Name: Fred Azar

Department:


Name: Albert Cerussi

Department:


Name: Ali Khamene

Department:


Name: Frank Sauer

Department:


Name: Bruce Tromberg

Department:

Country/Region
USA

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