Chiral Separation Medium
- Technology Benefits
- The invention also provides methods for preparing the enantioselective separation medium and electrochromatographic devices fabricated therewith.
- Technology Application
- This invention relates generally to the field of electrochromatographic separation, and more particularly relates to a novel enantioselective separation medium comprised of a monolithic, chiral, ionizable copolymer.
- Detailed Technology Description
- None
- Supplementary Information
- Patent Number: US6616825B1
Application Number: US2000645079A
Inventor: Fréchet, Jean M. J. | Svec, Frantisek | Lämmerhofer, Michael
Priority Date: 23 Aug 2000
Priority Number: US6616825B1
Application Date: 23 Aug 2000
Publication Date: 9 Sep 2003
IPC Current: B01J002029 | C07B005700 | C08F000246 | G01N0027447 | B01D001538 | G01N003000
US Class: 204605 | 204469 | 210656 | 522006 | 526256 | 526259 | 526260 | 52631844 | 526320
Assignee Applicant: The Regents of the University of California
Title: Electrochromatographic device for use in enantioselective separation, and enantioselective separation medium for use therein
Usefulness: Electrochromatographic device for use in enantioselective separation, and enantioselective separation medium for use therein
Summary: The device is used in conducting chiral electrochromatography (claimed).
Novelty: Electrochromatographic device for use in conducting chiral electrochromatography, comprises electrochromatographic conduit with enantioselective separation medium comprising monolithic, ionizable copolymer
- Industry
- Chemical/Material
- Sub Category
- Chemical/Material Application
- Application No.
- 6616825
- Others
-
Tech ID/UC Case
16987/2001-008-0
Related Cases
2001-008-0
- *Abstract
-
An electrochromatographic device is provided for conducting enantioselective separation of enantiomers. The device is comprised of a conduit containing a monolithic enantioselective separation medium, and may be, for example, a capillary tube or a microchannel in a substrate. The enantioselective separation medium is prepared by copolymerization of (a1) an ionizable chiral monomer or (a2) a chiral monomer and an ionizable comonomer, along with (b) a crosslinking comonomer and (c) a polymerization initiator, in (d) a porogenic solvent. Following ionization, the enantioselective separation medium serves as a charge carrier as well as a chiral separation medium, and further acts as an electroosmotic pump to facilitate the flow of a fluid. The invention also provides methods for preparing the enantioselective separation medium and electrochromatographic devices fabricated therewith.
- *IP Issue Date
- Sep 9, 2003
- *Principal Investigator
-
Name: Jean M. J. Frechet
Department:
Name: MICHAEL LAEMMERHOFER
Department:
Name: Frantisek Svec
Department:
- Country/Region
- USA
