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Device and method for the creation and implantation of non-circular cross section osteochondral allografts

Detailed Technology Description

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*Abstract

New Surgical Tools and Techniques to Make Patient Anatomy-Specific Osteochondral Grafts PossibleThe current invention developed by researchers at the University of Missouri (MU) includes the surgical instrumentation and method for creating custom anatomic osteochondral allografts (OCA) or autografts to treat damaged areas of joints. The revolutionary instrumentation allows for contouring of grafts to the patient’s anatomy and precise preparation of the recipient site for an OCA or autograft of complex geometry, rather than simple cylindrical grafts as currently performed. Between 600,000 and 900,000 patients in the U.S. undergo surgical treatment for articular defects resulting from osteochondritis dessicans, injury, trauma and osteoarthritis. Currently, surgeries using OCA or autograft comprise a small portion of the total number of procedures performed to treat these conditions due to their limitations. Though current allografts/autograft techniques are relatively easy to perform, they are not optimal for treating large articular defects in joints with complex geometries. The use of cylindrical grafts for these types of joint damage results in sub-optimal use of donor tissues, inability for anatomic reconstruction of defects, comprised graft stability, and removal of significant amounts of healthy cartilage in order to replace all damaged tissue. All of these downfalls can lead to unsuccessful outcomes for patients, such as graft failures and progression of disease, mainly due to the function of the non-patient-specific geometry of a standard cylindrical OCA or autograft. MU’s technology is predicted to overcome each of the pitfalls of current OCA and autograft procedures to improve outcomes and increase the number of patients that can be effectively treated with OCA and autografts.POTENTIAL AREAS OF APPLICATION-Human or veterinary orthopaedic surgery-Treating focal cartilage defects in joints MAIN ADVANTAGES OF INVENTION-Personalized allografts and autografts to match a patient’s joint geometry-Precise removal and replacement of damaged cartilage -Maximum preservation of healthy native tissue-Increased graft stability by utilizing a single continuous graft -Greater surgery success rateSTATE OF DEVELOPMENT: Completion of prototype; canine model testing ongoingLICENSING POTENTIAL: University seeks licensure with potential to commercializePATENT STATUS: Patent Application FiledTECHNOLOGY INNOVATORS: Ferris M. Pfeiffer, James L. Cook, James P. StannardTECHNOLOGY MANAGEMENT CONTACTSSamuel E. Bish, Ph.D.; bishs@missouri.edu; 573-882-5016

*Principal Investigator

Name: Ferris Pfeiffer, Assistant Professor

Department:

Name: James Cook, Associate Professor

Department:

Name: James Stannard, Professor & Chairman- Orthopaedic Surgery

Department:

Country/Region

USA