Bacteriophages to control Shigatoxigenic Escherichia coli
- Summary
- Divya Jaroni Ph.D., at Oklahoma State University has developed a systemto identify novel bacteriophage that are effective either singly or incombination against multiple strains of STECs, including O157, O45,O121, O145, O111 and O26. Dr. Jaroni has already isolated phages that have highlytic activity across multiple STEC strains, and are thermostable, pH stableand have a long shelf life. This technology will provide a natural and safealternative to current industry-pathogen-control-strategies.
- Technology Benefits
- • Thermostable• Ph stable• Storage stable at -80, -20 and 4 degrees• Strong inhibition of STECs• High lytic activity • Can reduce biofilm formation
- Technology Application
- • Food equipmentsterilization• Foodsterilization• Natural foodpreservative• Medical industry
- Detailed Technology Description
- None
- Countries
- Not Available
- Application No.
- None
- *Abstract
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None
- *Background
- Shigatoxigenic E. coli (STEC) isa major contributor to one in six Americans becoming sick due to a foodborneillness each year. Current methods often employ harsh chemical interventions toreduce STECs and are not optimally effective. From 2009-2013, 35% of 75foodborne illness outbreaks in ground beef were due to STECs. Clearly there isa need for novel methods to further reduce STEC outbreaks and illnesseffectively.
- *IP Issue Date
- None
- *IP Type
- Other Patent
- *Stage of Development
- Proof of concept.
- Country/Region
- USA

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