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Bacteriophages to control Shigatoxigenic Escherichia coli

Summary
Divya Jaroni Ph.D., at Oklahoma State University has developed a systemto identify novel bacteriophage that are effective either singly or incombination against multiple strains of STECs, including O157, O45,O121, O145, O111 and O26. Dr. Jaroni has already isolated phages that have highlytic activity across multiple STEC strains, and are thermostable, pH stableand have a long shelf life. This technology will provide a natural and safealternative to current industry-pathogen-control-strategies.
Technology Benefits
•      Thermostable•      Ph stable•      Storage stable at -80, -20 and 4 degrees•      Strong inhibition of STECs•      High lytic activity •      Can reduce biofilm formation
Technology Application
•      Food equipmentsterilization•      Foodsterilization•      Natural foodpreservative•      Medical industry
Detailed Technology Description
None
Countries
Not Available
Application No.
None
*Abstract
None
*Background
Shigatoxigenic E. coli (STEC) isa major contributor to one in six Americans becoming sick due to a foodborneillness each year. Current methods often employ harsh chemical interventions toreduce STECs and are not optimally effective. From 2009-2013, 35% of 75foodborne illness outbreaks in ground beef were due to STECs. Clearly there isa need for novel methods to further reduce STEC outbreaks and illnesseffectively.
*IP Issue Date
None
*IP Type
Other Patent
*Stage of Development
Proof of concept.
Country/Region
USA

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