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Aptamer-based selection for multiple cell surface markers in a single step

Summary
Milan N. Stojanovic, Ph.D.
Technology Benefits
Facilitates cell selection in a single stepIncreased selection affinity and selectivity compared to traditional antibodiesCan be applied to subcellular bodiesCan be utilized for delivery of pharmacological therapies following cell isolation/selectionPatent Information:Patents Pending Tech Ventures Reference: IR CU12229, IR CU15021, IR CU15072
Technology Application
Diagnostic tool for identifying and quantifying cellular phenotypes related to diseaseTool for fluorescence-based cell sorting and isolationAssay for disease detection and monitoringOrganelle-based diagnostics and therapeuticsTargeted pharmacological therapy for presenting a drug or other therapeutic agent to a target cell type
Detailed Technology Description
Milan N. Stojanovic, Ph.D.
*Abstract
None
*Inquiry
Jerry KokoshkaColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu
*IR
CU15021
*Principal Investigator
*Publications
Stojanovic MN, Stefanovic D. “ A deoxyribozyme-based molecular automaton” Nat Biotechnol. 2003 Sep;21(9):1069-74.Stojanovic MN, Stefanovic D, Rudchenko S. "Exercises in molecular computing" Acc Chem Res. 2014 Jun 17;47(6):1845-52.
Country/Region
USA

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