DNA logic gates create a low-cost, simple rabies assay which does not require sterile working conditions
- Technology Benefits
- -- Low-cost, easy to use assay to detect exposure to rabies removes the need for expensive, time-consuming PCR-based assays.-- Assay can be used in non-sterile environments characteristic of the developing world.-- Can distinguish between 7 different strains of rabies virus while existing technologies can only detect 6 of 7.Patent information: 2009/0275027 A1 ~ see link below.
- Technology Application
- -- Low-cost, easy to use assay to determine whether a person who has been bitten by an animal has been infected with rabies or related viruses.-- Use in non-sterile environments.-- Discrimination between rabies and related viruses.-- Detection of viral exposure immediately after an animal bite, as opposed to current technologies which can only detect after symptoms emerge and the disease is no longer treatable.-- Detection of other viral strains as DNA logic gates can be custom configured.
- Detailed Technology Description
- DNA logic gate automata that can detect 7 different strains of lyssavirus virus in a low-cost, rapid, easy to use assay which can be used in non-sterile settings.This technology is an automaton that comprises several DNA logic gates. Thes...
- *Abstract
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None
- *Inquiry
- Jerry KokoshkaColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu
- *IR
- 2862
- *Principal Investigator
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- *Publications
- -- J. Macdonald, Y. Li, M. Sutovic, H. Lederman, K. Pendri, W. Lu, B.L. Andrews, D. Stefanovic, and M.N. Stojanovic. Medium Scale Integration of Molecular Logic Gates in an Automaton. Nano Letters, Vol. 6, Issue 11, pp. 2598-2603. -- J. Macdonald, D. Stefanovic, and M.N. Stojanovic. DNA computers for work and play. Scientific American, Vol. 299, Issue 5, pp. 84-91.
- *Web Links
- USPTO: 2009/0275027 A1
- Country/Region
- USA
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