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Coronary Sinus Cannula with Left Ventricle Lead and Pressure Tent

Summary: Congestive heart failure is an expanding health concern, with more than 500,000 new cases each year. Cardiac resynchronization therapy (CRT) is effective in many of these patients. However, cannulation of the coronary sinus (CS), a critical step for lead insertion, is technically difficult and fails in 5-10% of attempts. Thus, there is a need for an improved cannula design as well as an alternative surgical technique that can simplify cannulation of the CS and improve the success rate of lead placement. This technology describes an improved coronary sinus cannula design and surgical approach for electrode placement.

Technology Benefits: Open thoracotomy under local anesthesia Lead insertion through open thoracotomy under local anesthesia Eliminates need for positive pressure ventilation during limited thoracotomy Reduced risk of bleeding during lead insertionA high degree of modularity and flexibility in pacing device design for each individualPatent Information:Patent Issued (US 8938310)Tech Ventures Reference: IR 2570, 2680, 2726

Technology Application: Placement of epicardial pacemaker leadsDeveloped technology could be adapted for other surgical procedures that utilize introducer/obturators to access intrapericardial space and cardiac chambersRPSM for CRT in patients who fail standard endocardial approaches RPSM for CRT in patients who are high risk candidates for thoracotomy because of adhesions RPSM for all known pacemaker and defibrillator leads in all patients

Detailed Technology Description: None

*Abstract: None

*Inquiry: Sara GusikColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu

*IR: 2726

*Principal Investigator

*Publications: Wang DY, Richmond ME, Quinn TA, Mirani AJ, Rusanov A, Yalamanchi V, Weinberg AD, Cabreriza SE, Spotnitz H. Optimized temporary biventricular pacing acutely improves intraoperative cardiac output after weaning from cardiopulmonary bypass: a substudy of a randomized clinical trial. J Thorac Cardiovasc Surg. 2011;141:1002-8.Wang DY, Gerrah R, Rusanov A, Yalamanchi V, Cabreriza SE, Spotnitz HE. Left ventricular pacing lead insertion via the coronary sinus cardioplegia cannula: a novel method for temporary biventricular pacing during reoperative cardiac surgery. J Thorac Cardiovasc Surg. 2011;142:73-6.

*Web Links: Patent pending: WO/2011/005814

Country/Region: USA

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