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A diagnostic and therapeutic target for brain tumor

Technology Benefits

The technology provides a therapeutic target directly relevant to high-grade gliomas: new drug or treatment can be developed with fewer side effects and more efficiency and specificity; new diagnostic test can be developed with more accuracy.

Technology Application

The technology can used to develop novel diagnostic test for high-grade gliomas, based on the expression of the transcription factors The technology can used to develop specific therapy for high-grade gliomas by inhibiting or interfering the expression of the transcription factors

Detailed Technology Description

The technology identified a pair of transcription factors that are master regulators of the mesenchymal state of brain cells, which is responsible for the development of high-grade gliomas in humans. The technology showed that this pair of transcript...

Country/Region

USA

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