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Methods for identifying compounds that inhibit the binding of p75 to FAP-1

Summary
Lead Inventors: Taka-aki Sato A composition capable of inhibiting specific binding between a signal-transducing protein and a cytoplasmic protein is described. A method of identifying a compound capable of inhibiting specific binding between a signal-transducing protein and a cytoplasmic protein is also disclosed. The composition in effective amounts may be used to induce apoptosis in cancer cells and thereby inhibit the spread of cancer. The composition also finds use in inducing apoptosis in virus infected cells.Compositions that can serve as effective signal mediators of apoptosis have been disclosed.
Detailed Technology Description
A composition capable of inhibiting specific binding between a signal-transducing protein and a cytoplasmic protein is described. A method of identifying a compound capable of inhibiting specific binding between a signal-transducing protein and a cyt...
*Abstract
None
*Inquiry
Jerry Kokoshka Columbia Technology Ventures Tel: (212) 854-8444 Email: TechTransfer@columbia.edu
*IR
570
*Principal Investigator
*Web Links
Patent number: EP0935467USPTO
Country/Region
USA

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