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FAT2 (Protocadherin 30) Monoclonal Antibody (8C5)

Detailed Technology Description: Project #: D1995-21Antigen Specificity: Protocadherin 30 (PCDH30)Clone: 8C5Host species: MouseReactive species: HumanDescription:FAT2 (FAT tumor suppressor homolog 2), also known as CDHF8, HFAT2 or MEGF1 (multiple epidermal growth factor-like domains 1), is a single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins. The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell to cell binding that is critical for the maintenance of structure and morphogenesis. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT2 contains one Laminin G-like domain, two EGF-like domains and 32 cadherin domains and is believed to function as a cell adhesion molecule.Applications: Western blot, Immunofluorescence, Immunoprecipitation

*Abstract

*Principal Investigator: Name: Margaret Wheelock, Professor
Department: Biology

Name: James Wahl
Department: Department of Oral Biology

Name: Keith Johnson, Professor
Department: Oral Biology

Country/Region: USA

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