Purification of Small RNAs from Human Biofluids
- Detailed Technology Description
- This invention provides methods for isolating circulating small RNAs from plasma/urine, CSF, or tissue samples, the method comprising using an alkaline phenol:chloroform extraction, and methods of use
- Countries
- Not Available
- Application No.
- None
- *Abstract
-
This invention provides methods for isolating circulating small RNAs from plasma/urine,CSF, or tissue samples, the method comprising using an alkaline phenol:chloroform extraction, and methods of use thereof, including for the detection, prognosis, and/or monitoring of disease in a subject. These methods significantly increase the yield of many assayable small RNAs such as miRNA, some by tenfold or more over present standard methods.
- *IP Issue Date
- None
- *IP Type
- Other Patent
- Country/Region
- USA

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