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High-Speed Multispectral Discrimination Technology, Flow Cytometry

Summary
Purdue University researchers have developed a new technology that allows high speed analysis of single particles for classification. Characteristics of this technology include advanced spectral analysis, high speed detection, and single particle discrimination capabilities. The basic principles of flow cytometry, image collection systems, image analysis, and signal processing are utilized. This technology's advanced detectors, signal separation processes, and analytical processes combine to provide new opportunities for cellular classification systems, such as clinical pathology, analytical cytology, or advanced pharmaceuticals in cellular systems.
Technology Benefits
High-speed detection of multiple labeling molecules and single particle discrimination capabilitiesReduces size and cost of systemsAllows greater versatility in fluorescent combinations
Technology Application
Medical/HealthDiagnostics
Detailed Technology Description
J. Paul Robinson
Countries
United States
Application No.
7,280,204
*Abstract

*Background
Current fluorescence intensity-based techniques are well-established in traditional screening methods that are used in diagnostic instruments. These methods rely on organic fluorochromes and emission band-detection systems. Although very powerful, they are restricted to approximately one dozen simultaneous fluorescent probes due to their design. Complex spectral compensation, complicated and numerous optics, and restricted spectral bandwidths make the current technology less efficient than desired.
*IP Issue Date
Oct 9, 2007
*IP Type
Utility
*Stage of Development
Process Validation in Lab
*Web Links
Purdue Office of Technology CommercializationPurdueInnovation and EntrepreneurshipJ. Paul Robinson
Country/Region
USA

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