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Antibody Against Influenza Protein M2

Technology Benefits
Validated foruse in Western blot, immuoprecipitation, immunofluorescence andimmunohistochemistry experiments
Detailed Technology Description
Antibody that recognizes the M2 transmembrane protein of influenza virus#researchtool #antibody
*Abstract

Northwestern researchers have developed a monoclonal antibody for detection of the influenza M2 protein (clone 14C2). This protein is vital for viral infection of host cells and as such has been a target of many research efforts since its discovery. This antibody has been successfully used to detect M2 via several standard experimental techniques and is expected to continue to contribute to influenza research efforts.

*Inventors
Robert Lamb
*Publications
Pinto LH, Dieckmann GR,Gandhi CS, Papworth CG, Braman J, Shaughnessy MA, Lear JD, Lamb RA, DeGrado WF(1997) A Functionally Defined Model for the M2 Proton Channel of Influenza AVirus Suggests a Mechanism for Ion Selectivity, PNAS. 94: 11301-11306.
Country/Region
USA

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