Thermoresponsive, Biodegradable, Elastomeric Material
- Detailed Technology Description
- None
- *Abstract
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Injectable hydrogels may be useful as a delivery vehicle/scaffold for cell transplantation. The thermosensitive polymer hydrogel that has been developed is: 1) Injectable at low (e.g. room) temperature; 2) Capable of binding biomolecules such as collagen and other bioactive factors (e.g. growth factors, differentiation factors); 3) Highly flexible and relatively strong at body temperature for use in soft tissue engineering; 4) Characterized by an LCST lower than 37oC before degradation, such that it can form a gel at body temperature; and 5) Characterized by an LCST higher than 37oC after degradation, so that the degradation product can dissolve in the bodyΓÇÖs aqueous environment and be cleared. Non provisional and PCT Patent Applications Filed
- *Principal Investigator
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Name: Jianjun Guan
Department: Med-Surgery
Name: William Wagner, Assistant Professor of Surgery
Department: Med-Surgery
- Country/Region
- USA
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