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An artemisinin derivative for the Treatment of CMV Viral Infections. (Hadasit)

Summary

Novel approach for the treatment of Cytomegalovirus (CMV) infection. The technology addresses unmet medical need in the field of CMV management. The use of currently available anti-CMV drugs is limited due to toxicity, low oral bioavailability and drug resistance.We have a pre- clinical proof of concept demonstrating the utility of a small molecule as an anti-viral agent (NDA will be required to disclose the identity of our candidate compound). The compound was also proven to be safe and efficacious in a phase I-II clinical study conducted by a major biopharmaceutical company for another indication.

Technology Benefits

Novel, orally administered, potent and safe, anti - HCMV drug for the prevention and treatment of HCMV infection.

Technology Application

Treatment and prevention of human cytomegalovirus infection. Prophylaxis & treatment in transplant patients. Treatment of symptomatic and asymptomatic congenital infection. Prevention of maternal-fetal transmission in pregnant woman. Treatment of symptomatic infection in healthy individuals.

ID No.

8-2010-21

Country/Region

Israel

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