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Monoclonal Antibodies Against Spc24/25 (Clone 2A10)

Technology Benefits

Specific antibody to detect SPC24 and SPC25 by antibody-antigen complex formation.

Technology Application

Immunocytochemistry/immunofluorescence Immunoprecipitation Western blot

Detailed Technology Description

SPC24 and SPC25 act as components of the essential kinetochore-associated NDC80 complex. This complex is required for chromosome segregation and spindle checkpoint activity. SPC24 and SPC25 are required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The described mouse antibody binds to human SPC24 and SPC25 and has been described for use in immunocytochemistry/immunofluorescence, immunoprecipitation, and western blot.

Others

Additional Technologies by these Inventors

Tech ID/UC Case

25542/2011-378-0

Related Cases

2011-378-0

Country/Region

USA

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