Monoclonal Antibodies for Laminin-5 and Hemidesmosomes
- Technology Benefits
- High Specificity
- Detailed Technology Description
- Monoclonal antibody portfolio specific to different subunits of laminin-5 and hemidesmosomes.#researchtool #antibody
- *Abstract
-
A Northwestern researcher has developed a multitude of monoclonal antibodies that recognize integral components involved in the interaction between epithelial cells and the extracellular matrix (ECM). His antibodies are specific to different subunits of laminin-5, a component of basement membranes, as well as HDs, a specialized cell-ECM contact that mediates the attachment of epithelial cell's basal surface to the ECM. These antibodies may be used as a research tool to study various features of epithelial cells that are pertinent to the process of wound healing, including motility, adhesion, proliferation, and cytoskeleton formation.
- *Inventors
- Jonathan Jones
- Country/Region
- USA
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