Multimodal Diagnostic Technology for Early Stage Cancer Lesions
The composition:ΓÇóComprises a plurality of metallic nanoparticles (2-30 nm) suitable for functionalization with target specific binding agents (such as antibodies, fab fragments, or binding fragments thereof), wherein such nanoparticles are attached to a polymeric carrier (500 nm to 10 microns) having encapsulated imaging agents for generating detection signalsΓÇóAllows for further coating of polymeric carriers with a hydrophilic gelling material, which may be biodegradable or biocompatible in natureΓÇóEffectively detects a cell/tissue morphology as compared to conventional compositionsΓÇóEnables an early diagnosis of superficial tumor lesions as compared to conventional compositionsΓÇóWould be commercially useful for diagnosis of various cancer types such as oral, esophageal, stomach, and colon
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USA