Animal models of human diseases of the CNS occupy a central role in drug discovery yet these models fail to yield new insights and efficacious drugs for the treatment of these diseases, in a field having a collective economic cost of over $40 billion per year. The number of CNS drugs reaching approv.....
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Interleukin 17 (IL-17) represents a family of pro-inflammatory cytokines consisting of six members, termed IL-17A-F. IL-17A is expressed by a unique lineage of CD4 T cells (Th-17) and is known to stimulate fibroblasts, endothelial cells, epithelial cells and macrophages to produce multiple pro-infla.....
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An innovative technique to preserve and prolong shelf-life in crop-plants cost-effectively. Different agricultural crops from Solanaceous species which include tomato, potato and eggplant, overcome oxidative stress by the production of steroidal glycoalkaloids (SGAs) and steroidal saponins. Although.....
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