亞洲知識產權資訊網為知識產權業界提供一個一站式網上交易平台，協助業界發掘知識產權貿易商機，並與環球知識產權業界建立聯繫。無論你是知識產權擁有者正在出售您的知識產權，或是製造商需要購買技術以提高操作效能，又或是知識產權配套服務供應商，你將會從本網站發掘到有用的知識產權貿易資訊。

返回搜索結果

Protein Knockout Platform

詳細技術說明

Methods to eradicate proteins at mRNA and protein levelsKitscomprising engineered SCF ubiquitin ligase and corresponding siRNA

其他

Published US Patent Application US20130011920
Zhou P, et al Harnessing the ubiquitination machinery to target the degradation of specific cellular proteins. Mol Cell. 2000 Sep;6(3):751-6 (Pubmed 11030355)
Zhang J, Zheng N, Zhou P. Exploring the functional complexity of cellular proteins by protein knockout. PNAS. 2003 Nov 25;100(24):14127-32. (Pubmed 14593203)
Cong F e al. A protein knockdown strategy to study the function of beta-catenin in tumorigenesis. BMC Mol Biol. 2003 Sep 29;4:10. (Pubmed 14516475)
Cohen JC et al Transient in utero knockout (TIUKO) of C-MYC affects late lung and intestinal development in the mouse. BMC Dev Biol. 2004 Apr 16;4:4. (Pubmed 15090077)
Zhou P. Targeted protein degradation. Curr Opin Chem Biol. 2005 (Pubmed 15701453)

國家/地區

美國

欲了解更多信息，請點擊這裡