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Acoustically Triggered Nano/Microscale Propulsion Devices

技術應用

Applications of the invention include in vivo drug delivery, artery cleaning, biomolecular/cellular delivery, tissue sampling, crossing the blood/brain barrier, tissue penetration for triggering immune responses and/or targeted gene regulation schemes.

詳細技術說明

University researchers have developed new nano/microscale propulsion devices (NMSPD) that utilize ultrasound to externally trigger on-board fuel (i.e., perfluorocarbon emulsions), bound within the device interior, for ultrafast NMSPD propulsion. The invention includes methods of fabricating the NMSPD devices. The NMSPDs are biocompatible and accelerate quickly, reaching high average velocities (> 6 m/s) that are more than 100 times faster than conventional micromachines. The high thrust of the devices enables piercing, puncturing, deep penetration, deformation, and tearing apart of tissue (e.g. when fired into lamb kidney sections). Firing can also be oriented magnetically and multiple NMSPDs can be fired simultaneously. The core technology is scalable and flexible in terms of shape, design, materials used, fabrication process and external triggering source.

附加資料

Inventor: WANG, Joseph | ESENER, Sadik C. | KAGAN, Daniel | BENCHIMOL, Michael | CLAUSSEN, Jonathan
Priority Number: WO2013123524A1
IPC Current: B82B000100 | B81B000300 | F03G000700
Assignee Applicant: The Regents of the University of California
Title: ACOUSTICALLY TRIGGERED NANO/MICRO-SCALE PROPULSION DEVICES | DISPOSITIFS DE PROPULSION À L'ÉCHELLE NANO/MICROSCOPIQUE DÉCLENCHÉS DE MANIÈRE ACOUSTIQUE
Usefulness: ACOUSTICALLY TRIGGERED NANO/MICRO-SCALE PROPULSION DEVICES | DISPOSITIFS DE PROPULSION À L'ÉCHELLE NANO/MICROSCOPIQUE DÉCLENCHÉS DE MANIÈRE ACOUSTIQUE
Summary: The ultrasound responsive propulsion device is useful for implementing acoustically triggered propulsion of nano and micro scale structures.
Novelty: Ultrasound responsive propulsion device used for implementing acoustically triggered propulsion of nano structures, has tube with inner layer having electrostatic surface coupled with ultrasound-responsive substance to form bubbles