A Method to Generate Novel Bioactive Molecules
UC San Diego inventors have invented a very general method to design and create new compounds with anti-bacterial, anti-fungal, anti-cancer, or other bioactive properties. Different from the existing art, where the biological effect of a compound must be determined, this invention allows for compounds to be designed and created with these effects known a priori. For example, this shortcoming, which the current invention overcomes, is part of the existing art being applied to anti-bacterial synthesis—such as mutational biosynthesis, genetic engineering, structure-based drug design, or interrogation of novel natural products.Slide Show Presentation
Patent Number: US20130211100A1
Application Number: US13825792A
Inventor: Palsson, Bernhard | Charusanti, Pep
Priority Date: 29 Oct 2010
Priority Number: US20130211100A1
Application Date: 1 May 2013
Publication Date: 15 Aug 2013
IPC Current: C12Q000118 | C12N000120
US Class: 548453 | 43500611 | 435032 | 4352535
Title: Method to Generate Novel Bioactive Molecules
Usefulness: Method to Generate Novel Bioactive Molecules
Summary: The methods are useful for identifying a bioactive compound in a culture; and for identifying a genomic mutation in an organism (all claimed).
Novelty: Identifying a bioactive compound in a culture comprises co-culturing two or more organisms, detecting inhibition of growth of the target organisms, and detecting the presence of one or more bioactive compounds in the co-culture
生物醫學
DNA /基因工程
9080199
State Of Development Experimental work to create a positive bioassay has been completed and the invention is already being applied to the creation of novel anti-bacterial agents. Other Information Access the recommendation on F1000 Prime Tech ID/UC Case 19978/2008-230-0 Related Cases 2008-230-0
美國
