Complex Optical Encoding of Porous Silicon Photonic Crystals
Researchers at UC San Diego have invented a method of optically encoding porous silicon photonic crystals for use in high throughput screening and bioassays. The method allows for large libraries of unique particle types to be manufactured. The process is distinct from existing methods of encoding, such as fluorescent molecules, core-shell quantum dots, and photonic crystals formed using Rugate or Bragg reflectivity approaches, in that it does not strive to create spectral lines that act as bits-and are limited by the number of codes that can be generated. In contrast, this invention for data extraction and analysis utilizes all the complexity of the spectrum which results from the reflectivity properties of the photonic crystals. Unlike bioassay systems that couple fluorescent encoding methods with fluorescent assay, the method does not suffer from spectral overlap of the encoding method with the assay readout. These photonic crystals may be used as integral parts of randomly assembled microarrays. These microarrays could be applied in the field of gene expression, genotyping, proteomics, as well as real time chemical and biological sensing.
Patent Number: US20070148695A1
Application Number: US2003583920A
Inventor: Sailor, Michael, J. | Meade, Shawn, O.
Priority Date: 7 Feb 2002
Priority Number: US20070148695A1
Application Date: 20 Jun 2006
Publication Date: 28 Jun 2007
IPC Current: C40B003006 | C40B004008 | C40B006004
US Class: 4350071 | 4352872 | 506009 | 506022 | 977902
Title: Optically encoded particles, system and high-throughput screening
Usefulness: Optically encoded particles, system and high-throughput screening
Summary: The invention is for producing an optically encoded particle library for identification of analyte bound to encoded particle or identification of host (claimed).
Novelty: Production of optically encoded particle library for identification of analyte bound to encoded particle or identification of host, comprises selecting one of computer controlled waveforms, and applying computer controlled waveform
化工/材料
化工/材料應用
9181634
Related Materials Intellectual Property Info This technology is presently available for licensing. Patents pending. Tech ID/UC Case 19563/2003-214-0 Related Cases 2003-214-0
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