Relay Electrospray Ionization - Ultrasmall Volume Analysis for Mass Spectrometry
Researchers at Purdue University have developed a new method of electrospray for ultrasmall volume sampling and analysis known as the relay electrospray ionization technique. The design is focused upon the on-demand injection of electrically charged ions onto the outside surface of a nanocapillary. The resulting passage of electrical charge from the injected ions to the substance creates an immediate electrospray from the capillary, resulting in no dead volumes. By moving secondary capillaries in an automated fashion, high throughput sample screening and analysis is enabled. Thus, the problems of the solution clinging to the apparatus, dead volume creation, the need for time consuming cleaning procedures to eliminate carryover, and small volume sampling are dealt with under this new system.
Samples exceptionally small amounts of matter accuratelyIntegrated, simplified small volume analysis On-demand, controlled chemical reactions in the primary and relay ion sources Eliminates carryover and time consuming cleaning procedures
Biology Chemical analysis Medical/Health
R. Graham CooksPurdue ChemistryAston Labs
United States
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