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Efficient Synthesis of HIV-1 Protease Inhibitors
總結
Researchers at Purdue University have developed a new series of hexahydrofuropyran-derived HIV-1 protease inhibitors for treatment of HIV infection and AIDS. These inhibitors are novel and remarkably potent, similar to Darunavir, an FDA approved inhibitor also developed at Purdue. They also show excellent activity against multiple PI-resistant variants, superior to other FDA approved inhibitors.
技術優勢
High antiviral potencyEffective against wide range of variants
技術應用
Medical/HealthcarePharmaceuticalsHIV/AIDS TreatmentDrug Development
詳細技術說明
Arun GhoshGhosh GroupPurdue Chemistry
國家
United States
申請號碼
9,024,038
國家/地區
美國
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