A Class of Novel and Nonpeptide HIV-1 Protease Inhibitors
Purdue University researchers have designed and synthesized a novel class of HIV-1 protease inhibitors containing isophthalamide derivatives for the treatment of multidrug-resistant strains of HIV. These potent nonpeptide inhibitors are expected to possess improved pharmacological properties, are easy to synthesize in quantities, and will be further applicable for new drug development.
Novel HIV therapeutics with improved pharmacological propertiesEffective for the treatment of multidrug-resistant strains of HIV Simple chemical synthesis amenable to large-scale production
Medical/HealthcarePharmaceuticalsHIV/AIDS TreatmentDrug Development
Arun GhoshGhosh GroupPurdue Chemistry
United States
9,085,571
美國
