Method of Using Rhein for Treating or Preventing Sonic Hedgehog Signaling-Related Disease or Disorder
The present invention relates to a method of using rhein in treatment and/or prophylaxis of sonic hedgehog signaling-dependent disease or disorder.
Providing a pharmaceutical composition comprising a therapeutically effective amount of rhein for treatment and/or prophylaxis of disease or disorder depending on sonic hedgehog signaling pathway.
For the treatment and/or prophylaxis of the disease or disorder
The present invention relates to the method of using a therapeutically effective amount of anthraquinone derivative, namely 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid, also known as rhein, as an inhibitor of sonic hedgehog signaling pathway for the treatment and/or prophylaxis of the disease or disorder depending on the signaling pathway such as fibrotic conditions, stellate cell-related pathologies, inflammatory activities and/or proliferative diseases including tumors and adenocarcinoma.
診斷/治療
其他疾病
2013.08.09
US 13/962,977
Filed
A61/BZ/Rshh/US01
香港
