Methods For Enhancing The Production Of Interferon In Cell Culture
Methods For Enhancing The Production Of Interferon In Animal Cell Culture Are Described. These Methods Rely On The Manipulation Of The Cellular Levels Of Certain Inducers Of Interferon Production, In Particular Cellular Levels Of Double-Stranded-Rna-Dependent Kinase (Dsrna-Pkr, Or Pkr). In Cell Cultures That Overproduce Pkr, Interferon Synthesis Is Induced To High Levels, And Significant Amounts Of Interferon Can Be Recovered Without Conventional Induction Of Interferon By Virus.
Patent Number: AU199668576A
Application Number: AU199668576D
Inventor: LAU ALLAN S
Priority Date: 22 Aug 1995
Priority Number: AU199668576A
Application Date: 22 Aug 1996
Publication Date: 19 Mar 1997
IPC Current: C12N001509 | A61K003912 | A61K0039125 | A61K0039145 | A61K0039205 | C07K001447 | C07K0014555 | C12N000700 | C12N000701 | C12N000912 | C12N0015113 | C12N001519 | C12N001567 | C12P002102 | C12Q000118 | C12Q000170 | A61K003800 | C12R000191
Assignee Applicant: Univ California
Title: Methods for enhancing the production of interferon in cell culture
Usefulness: Methods for enhancing the production of interferon in cell culture
Summary: USE The method is useful for prodn. of high levels of interferon without conventional induction of interferon by virus.
Novelty: Prodn. of interferon in animal culture without conventional viral induction by over-prodn. of double-stranded RNA-dependent kinase in cell culture
功能設計
機械結構
香港
