Therapeutic Hydrogels of Nonsteroidal Anti-Inflammatory Drugs
· Oligopeptidescomprising D-amino acids to replace L-amino, produce protease resistant motifs
Bio stableand biocompatible supramolecular hydrogels of D-peptides and therapeutic smallmolecules increase target selectivity and decrease adverse drug reactionsTheinvention confers proteolytic resistance and preserves drug activity forsustained releaseAdministered as topical gels or creams to use for relieving pain induced bylocal inflammationThetherapeutic hydrogels serve as a cheap, safe, and effective carrier for drug toreduce ADRsThesynthetic route for said peptidic conjugate is facile, well established, andeasy to scale up
Therapeutic Hydrogels of Nonsteroidal Anti-Inflammatory Drugs:D-peptides/NSAIDs conjugates boost drugselectivity and reduce side effects
United States
14/441,773
美国
